Research

During my time at Pitt, I have been fortunate to engage in 1) collaborative work with a nursing research mentor, 2) original work researching global health (specifically non-communicable diseases), and 3) data analysis for research projects and publications in peer-reviewed journals.

1) My collaborative work with my nursing research mentor has focused on cardiovascular disease, diabetes, sleep, and occupational health. We have conducted research in multiple forms – from literature reviews to creating participant recruitment fliers, from quantitative statistical analyses to qualitative reviews, from engaging participants with advanced chronic diseases to participants who are nurses in the healthcare setting. My research mentor and I have communicated our ideas both in-the-office and using technology. This has been a great opportunity for me to learn how to communicate in a professional setting. Research with my mentor has given me a chance to see how the scientific process progresses from beginning to end … and back to beginning again.

2) My global health research has focused on non-communicable diseases, specifically ischemic heart disease and type 2 diabetes mellitus. I completed a review of the literature to explore how risk factors for these conditions are similar and vary in different regions of the world. After this project, I would like to look at communicable diseases around the globe. The COVID-19 Pandemic has certainly taught us all that both communicable and non-communicable diseases occur everywhere in the world; while some places are certainly more affected than others and need specific interventions, there is also a great need for global awareness and collaboration. My global health research has allowed me to recognize diverse topics and the need to integrate interdisciplinary findings.

3) My analyses for research publications has focused on the genetics of diabetes and obstructive sleep apnea as well as wearable activity monitors. My co-authors and I have written reports of our quantitative analyses as well as reviewed published literature for studies’ use of activity monitors. I have presented my research in public forums as well. These have been at national and international conferences, including nursing organization conferences as well as interdisciplinary engagements. My research publications and presentations have given me the opportunity to learn about research dissemination and the importance of “getting the word out,” so evidence-based change and best practices can be implemented in everyday life.

Research Projects

  • DNA Methylation Changes and Sleep Quality

    Exploring the impact of sleep on the genetics of those with diabetes and obstructive sleep apnea

    Citation: Bigini EG, Chasens ER, Conley YP, & Imes CC. DNA methylation changes and improved sleep quality in adults with obstructive sleep apnea and diabetes. BMJ Open Diabetes Research and Care 2019;7:e000707. doi: 10.1136/bmjdrc-2019-000707

  • Wearable Activity Monitors

    Activity monitors and physical activity, sedentary behavior, and sleep

    Citation: Cajita MI, Kline CE, Burke LE, Bigini EG, & Imes CC. Feasible but not yet efficacious: A scoping review of wearable activity monitors in interventions targeting physical activity, sedentary behavior, and sleep. Current Epidemiology Reports 2020;1-14. doi: 10.1007/s40471-020-00229-2

  • Nurses' Dietary Assessments

    Exploring differences in self-reported dietary intake among nurses with rotating shifts

    Bigini EG, & Imes CC. 24-Hour Dietary Assessments in Rotating Shift Nurses. 2020 National Council of Undergraduate Research (accepted and prepared; conference canceled due to COVID-19)

  • Non-Communicable Diseases in Global Health

    Similarities and variations in heart disease and diabetes risk factors across the globe

    Bigini EG. Risk Factors for Heart Disease and Diabetes in Low-/Middle-Income versus High-Income Countries: Overlaps and Variations. 1) 2019 National Council of Undergraduate Research; 2) 2018 Independent Study Presentation

  • Diabetes Education, Sleep, and Genetics

    Relationships between diabetes education, sleep, and gene methylation in participants with diabetes and obstructive sleep apnea

    Bigini EG, Chasens ER, Conley YP, & Imes CC. Diabetes Education is Associated with Improved Sleep Quality and Changes in Gene Methylation. 1) 2017 International Society of Nurses in Genetics World Congress; 2) 2018 National Student Nurses’ Association Convention